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Inclusion criteria selected for patients with a diagnosis of epilepsy, an average of at least 2 seizures per month over the preceding 3 months prior to starting MAD, at least 18 years of age at the time of enrollment, having baseline carnitine lab measurement prior to starting MAD, and at least one carnitine lab measurement at a follow-up timepoint

Apperloo EM, Neuen BL, Fletcher RA, et al

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For example, colitis may develop into colon cancer after inflammatory infiltration, increased production of ROS, impairment of antioxidant defenses, DNA damage, and genetic and epigenetic alterations, resulting in the transformation of epithelial cells [234]