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Analysis in the Broad Institute's Connectivity Map showed GHK modulates expression of ~4,000 human genes roughly 31% upregulated, 63% downregulated with consistent shifts in DNA-repair, antioxidant defense, inflammatory signaling, and fibrotic pathways

doi: 10.1016/j.redox.2024.103143 59 BaoTLiaoTCaiXLuBDaiGPeiSet al

Suspected side effects from medicines including those received as part of a clinical trial can be reported to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk