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3.7.3 Mechanisms of association between UPF intake and ASD There have been a range of recent studies that have shown that high dietary intake of UPF may contribute to an increased risk of developing ASD, which may be mediated through a range of different pathophysiological mechanisms, including lipid dysregulation, oxidative stress and neuroinflammation (Table 2)

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J Neurosci Methods 343:108827 z G, Deelchand DK, Wijnen JP, Mlynarik V, Xin L, Mekle R et al (2021) Advanced single voxel 1H magnetic resonance spectroscopy techniques in humans: experts consensus recommendations

In clinical practice, oral pigmentation discovered incidentally during evaluation for another condition is a well-recognized scenario