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What are the risks of switching from semaglutide to tirzepatide

"Lilly's Once-Weekly Dulaglutide Shows Non-Inferiority to Liraglutide in Head-to-Head Phase III Trial for Type 2 Diabetes" (Press release)

This is a common source of confusion because both are considered next-generation incretin mimetics, yet they act on completely different receptor pathways

26 The majority (67%) of the patients reviewed had a mean baseline HbA1c of 9.5% when therapy was initiated, which supports the theory of lack of action in response to abnormal findings