These genetic factors influence baseline appetite regulation, metabolic rate, and how your body responds to dual-receptor activationbut they represent predispositions, not certainties
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Warning signs that warrant prompt medical attention include: Severe or persistent abdominal pain , especially if radiating to the back and accompanied by vomiting (may indicate pancreatitis, which is a serious side effect mentioned in the Mounjaro SmPC) Persistent nausea, vomiting, or right upper abdominal pain (may indicate gallbladder disease, another potential side effect of Mounjaro) Severe or persistent diarrhoea lasting more than 48 hours Signs of dehydration : extreme thirst, dark urine, dizziness, confusion, or reduced urine output Persistent vomiting that prevents adequate fluid or food intake Blood in stools or black, tarry stools Symptoms of electrolyte imbalance : muscle weakness, irregular heartbeat, or numbness and tingling For severe symptoms, patients should contact NHS 111 or attend an urgent treatment centre or A&E, particularly if they suspect pancreatitis or severe dehydration