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Shapiro-Wilk test for normality was performed and for data sets returning normal distribution, t test was used when comparing two groups and one-way analysis of variance (ANOVA) followed by post-hoc Tukeys multiple pairwise comparisons was used when comparing more than two groups

Note: Not intended to treat or prevent alcohol-related illness or hangovers

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A comparative analysis was conducted using disproportionality analysis, reporting odds ratio (ROR), and stratified analysis methods to assess and compare the signals of adverse events (AE) and the time to onset of adverse reactions associated with different routes of administration of semaglutide from 2017 to 2023