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Structural rebuilding depends on: Adequate blood flow so repair materials can reach the site Proper cellular migration so rebuilding is organized Inflammation control so tissue is not continually degraded When GHK-Cu is used alone, you may see improvements in texture and appearance, yet deeper functional recovery can lag when the rest of the repair system is not supported

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DAPA therapy achieved significant improvements in 3% ODI only in the group of moderate/severe SDP (25.0 3.8 at baseline versus 18.5 6.1 at the end of the study, p = 0.017)