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Common ingredients in pre-workouts include: L-Citrulline Small studies using lower doses of L-citrulline malate have shown some improvements in cycling performance and muscle soreness, though some larger-scale meta-analyses of aerobic performance have revealed mixed results, even with higher doses.35 36 Other large reviews have been more positive, especially at 8g/day and above.45 The trend in the literature seems to indicate that higher doses would be more effective, though many pre-workout supplements offer 6g or less

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Researchers reviewed 51 studies that indicated pharmacists and technicians experience up to 20 interruptions per hour