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However, the need for multiple doses can also be a drawback for some, as it requires careful planning and adherence to a schedule to avoid lapses in effectiveness
Thymosin beta 4 is also one of few compounds in this class with genuine randomised controlled human data, though in a topical ophthalmic formulation rather than a systemic one, RGN-259 eye drops having been evaluated in placebo-controlled Phase 2 and Phase 3 trials (Sosne et al., Cornea 2015 and Int J Mol Sci 2023)
Providers often recommend lifestyle optimization first, with biomarker re-assessment after 812 weeks before escalating to targeted supplementation
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