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The peptide that allows them to do this is called Exendin-4 and is strikingly similar in both structure and function to human GLP-1

Extensive research and clinical trials have demonstrated that GLP-1 medications are generally safe for both short-term and long-term use

As we go through menopause, our estrogen levels dramatically decrease, and this is what causes symptoms

In addition to acting through the p38 pathway, GLP-1RAs also promote the increase of PKA levels via the cAMP-dependent pathway, which in turn prevents the phosphorylation of epidermal growth factor receptor (EGFR) and activator of transcription 3 (STAT3), resulting in the inactivation of the EGFR-STAT3 signaling pathway in tumor cells and subsequently downregulating several downstream effector genes such as myelocytomatosis oncogene (c-Myc), survivin, cyclin D1, Bcl-xl, and Bcl-2, thereby inducing apoptosis in tumor cells in a dose-dependent manner [70, 73]