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So dose/volume tunes you from ~50% 70% 5AR2 inhibition locally, with varying systemic spillover

doi:10.1097/00003246-199906000-00028 2020 The Author(s)

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Pneumonia is associated with kidney complications including end stage renal failure (Huang 2014), and studies have linked pneumonia to increased risk of arrhythmias, heart attack, and worsening of heart failure (Musher 2012