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[114] randomized subjects to semaglutide or placebo to observe the change of liver fat from baseline to week 48, and found that semaglutide significantly reduced hepatic steatosis, improved liver enzymes and metabolic parameters, and had a positive effect on the diagnosis and treatment of NAFLD compared with placebo

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During ox-LDL-induced endothelial injury, SREBP-1/stearoyl-CoA desaturase 1 (SCD1)/fatty acid desaturase 2 (FADS2) expression decreased and participated in ferroptosis processes

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