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Atrial fibrillation is associated with decreased total cerebral blood flow and brain perfusion

The paracellular translocation of macromolecules up to 125 is carried out by a low-capacity leak pathway regulated by zonula occludens (ZO), occludins, and tricellulins (Odenwald and Turner 2017

doi:10.1016/j.molmet.2020.101102 15

While certain laboratory conditions show a depletion effect, the story is very different when it comes to daily wellness routines for healthy individuals