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So far, clinical trials have not shown any specific impact on sleep

Associations of serum T-GSH, GSSG, and GSH levels with clinical outcomes of treatment responders Based on a reduction rate of 25% in the PANSS total score after ECT as the criterion for clinical improvement, patients were classified as responders or non-responders

These results may inform research into psychiatric safety and potential repurposing opportunities for GLP-1RAs, especially in people with mental health disorders, but randomized clinical trials are needed to determine whether the genetic associations translate into treatment benefits