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Causes of proctitis include: An infection Certain medications Prior radiation therapy for cancer treatment Some forms of inflammatory bowel disease (IBD) Diagnosing Anal Bleeding They may: Feel for abnormalities within your rectum with a gloved, lubricated finger Examine your anus visually and using an anoscope during the physical exam Perform a colonoscopy for direct visualization of your colon, which is the gold standard for evaluation How is Rectal Bleeding Treated