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norepinephrine increases both total peripheral resistance, as well as systolic and diastolic blood pressure Note : Compensatory vagal reflexes tend to overcome the direct positive chronotropic effects on the heart (since both branches of the ANS innervate the SA node), but do not eliminate the positive inotropic effects on the ventricle (which does not have significant vagal innervation)

It can reduce the risk of serious cardiovascular complications in individuals with type 2 diabetes and heart disease

The study will enroll 24 adults from 30-65 years old with overweight or obesity

Always take CONTRAVE exactly as prescribed by your doctor