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Phase 2 Type 2 Diabetes Trial Rosenstock et al., The Lancet (2023) Rosenstock and colleagues conducted a phase 2, randomized, double-blind, double-dummy, placebo-controlled and active-comparator-controlled, parallel-group trial of retatrutide in adults with type 2 diabetes

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Currently, the ongoing FLOW is assessing whether or not semaglutide can inhibit worsening of CKD in patients with T2D ( Renal impairment defined as either an eGFR 5075 ml/min/1.73 m 2 and UACR 3005,000 mg/g or an eGFR 2550 ml/min/1.73 m 2 and UACR 1005,000 mg/g are included in this study

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