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Endocrine and Thermoregulation Support Some research suggests DSIP has regulatory effects on body temperature, luteinizing hormone (LH), and melatonin secretion , possibly contributing to its role in sleep and recovery

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6 They activate mitogen-activated protein kinase (MAPK) pathways that induce key regulators in late G1 phase such as Cyclin Ds and cyclin-dependent-kinases 4/6 (CDKs), which have a critical role in the control of the G1/S transition and the commitment to DNA replication

Here we summarize some of the most important achievements reached in this lively area of research