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The Mental and Physical Impact of Stopping Quitting GLP-1s isnt just about seeing the weight come back

The high rates of obesity and diabetes among PCOS patients receiving semaglutide and tirzepatide in this study are consistent with these metabolic features and suggest that GLP-1 RA therapy may play an expanding role in addressing the metabolic aspects of PCOS

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Next, cholesterol-stimulated INS-1 cells were treated with AMPK activator AICAR or PARP-1 overexpression alone or co-treated with AICAR and PARP-1 and examined for the protein levels of p-PARP-1 and ABCA1