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Additional research into other novel biomarkers to more precisely pinpoint MDD diagnosis could ultimately lead to a different way of thinking about treatments for MDD and other disorders. Rasgon adds: We are excited about this first translational study in humans, and poised to build on our results to identify new treatment targets in the brain.

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Tryptophan catabolites, inflammation, and insulin resistance as determinants of chronic fatigue syndrome and affective symptoms in long COVID