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(2015) investigated the gut-brain-kidney axis and revealed that CKD increases gut permeability, leading to the translocation of bacteria and their products, such as LPS, into the bloodstream

At the same time, Lactobacillus rhamnosus derived extracellular Vesicles can regulate the process of adipocyte metabolism, inhibit the excessive release of inflammatory factors, reduce the chronic inflammatory reaction of adipose tissue, and improve dyslipidemia (Tong et al., 2021)

In some cases, growth hormone therapy can help these children to reach a more normal height

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