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The proportion of participants achieving clinically meaningful weight reduction was also significantly higher with semaglutide: 79 percent achieved at least 5 percent weight loss 63 percent achieved at least 10 percent 50 percent achieved at least 15 percent 30 percent achieved at least 20 percent These outcomes were accompanied by significant improvements in physical function, as measured by a validated quality-of-life tool

The study protocol was approved by the Ethics Committee