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FDA Approved CJC-1295/Ipamorelin No Tesamorelin (Egrifta) Yes (November 2010) Mechanism CJC-1295/Ipamorelin GHRH analog + ghrelin receptor agonist (dual pathway) Tesamorelin (Egrifta) GHRH analog (single pathway) How It Works CJC-1295/Ipamorelin CJC-1295 extends GH release signal