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Therapeutically, the evidence favors node-specific, compartment-targeted interventionsNOX/NOS modulation, mitochondrial quality control and RET tempering, ER redox tuning, calibrated sulfur-axis support and iron/ferroptosis managementimplemented as time-staged sequences (acute subacute chronic) and guided by biomarker gates rather than symptoms alone

232,233 Epigenetic factors Increasing evidence indicates that ASD is the result of a complicated interaction between genes and the environment