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Symptoms of undermedication Less commonly, some patients may experience worsened hypothyroid symptoms if tirzepatide causes enough gastrointestinal disruption, through severe nausea or vomiting, to reduce their levothyroxine absorption on certain days

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By activating GLP-1 receptors, these medications help to slow gastric emptying, increase insulin secretion, and promote a feeling of fullness, all of which contribute to reduced calorie intake and weight loss