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Future studies therefore should envisage to identify HCV-HIV coinfected individuals in clinical cohorts allowing an in-depth characterization of immune status and the presence of HCV high replicator variants

Considerations: As with any copper-containing compound, there is a theoretical concern about copper toxicity with excessive systemic administration

However, its most fascinating and clinically relevant functions occur within the central nervous system, where it acts as a highly specialized dual-role neurotransmitter