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GLP-1 drugs target the GLP-1 trans-membrane receptor, which is one of a large family of G protein-coupled receptor (GPCR) proteins that straddle cell membranes and transduce chemical signals from outside the cell to its interior

For managing nociceptive pain, pharmacologic treatments include the administration of acetaminophen at a dosage of 500 mg every 6 h, with a maximum limit of 2 g per day

This overactivity in GBC cells is hereby inhibited, leading to reduced invasiveness and EMT, which is important for metastasis in cancer cells

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