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4.5 Disease heterogeneity and subtype-specific therapeutic strategies Endometriosis exhibits significant clinical and biological heterogeneity, encompassing diverse anatomical subtypessuperficial peritoneal endometriosis (SPE), ovarian endometriomas (OMA), and deep infiltrating endometriosis (DIE)each with distinct pathophysiological features, symptom profiles, and fertility implications (13)

Table 1 summarizes cases identified in PubMed using the search terms MMNST and malignant melanotic nerve sheath tumor that were published after the 2021 WHO CNS tumor classification, in which MMNST was designated a potentially aggressive condition

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In humans, decidualization coincides with the recruitment of uterine natural killer cells (uNK) to the uterus via local expression of chemokines such as CCL4, CXCL9, and CXCL10